The Problem


US Healthcare System: The emphasis on Curative measures.
   -  According to the Healthcare Cost Institute USA, in 2022 only 3.5% of total healthcare expenditures was dedicated to preventive care programs.
  -  U.S. life expectancy lags behind dozens of other nations—including Portugal, Slovenia, and Turkey—by as much as seven years
  -  According to the Centers for Medicare and Medicaid Services, “Total healthcare costs — including all private and public spending — are anticipated to rise from $4.7 trillion in 2023 to $7.2 trillion by 2031, growing by an average of 5.5 percent per year.”



GenoWise Solution

GenoWise is a comprehensive DNA assessment device developed with Nanopore technologies and integrated with compatible Bioinformatics and DNA databases for end-to-end DNA sequencing and analysis. The GenoWise software is an important component of the device, that contains application logic for data exchange to and from bioinformatics tools and databases, data storage and retrieval, GUI, and report generation. Tailored for the medical community, it is automated and comprises simple operations that do not require specialized lab skills, eliminating the need for multiple disparate processes for DNA assessment.

Our solutions is based on the following key features:

   -  Nanopore technology: for accurate DNA sequencing.
   -  DNA Library Preparation: Oxford’s VolTRAX technology for DNA library preparation suitable for DNA sequencing.
   -  Bioinformatics Tools: for DNA alignment with Reference Genome.
   -  Accessibility to public databases such as DisGeNET, GeneFood, and PharmGKB for data mapping and analysis.
   -  Regulatory Approvals: Our solution depends on obtaining regulatory approvals from FDA, and other governing organizations for manufacturing and selling medical devices. It also requires compliance with HIPAA for integration with patient’s Electronic Health Records.
   -  Integration with EHR: Our solution depends on a greater acceptance of DNA testing in primary care settings, and user consent for DNA testing and information and sharing.

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Meet The Team

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Atlas Long

Project Planner
 
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Jack Sadowski

Graphics Designer
 
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Luke Longin

Public Relations
 
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Rishi Mishra

Programmer
 

Our Engagements

University of North Carolina Charlotte

Mecklenburg County Health Department

Levine Cancer
Institute

Palmentto Medical
Group

Community Benefits

Useful health insights

Empower individuals with crucial health information for making proactive lifestyle and healthcare decisions, thereby reducing dependency on healthcare resources. A greater understanding of one’s health can provide a sense of relief and help prepare better for the future.

Genomic medicine

Our solution can expedite development of genomic medicine, offering hope to newborns and children born with congenital diseases. The recent breakthrough in gene-editing technology, CRISPR, even raises the prospect of directly modifying DNA that causes debilitating diseases. It will help usher in an era where one can choose to alter a genetic disadvantage and live a fulfilling life, instead of accepting a predetermined fate.

Early Disease Detection and Prevention

Some diseases exhibit non-specific symptom making it difficult to diagnose until the disease has progressed. Our solution can help detect abnormalities early on by identifying DNA mutations, that can lead to early investigation and detection.

Early intervention, Tailored Treatment Plan

Access to genetic data can assist doctors in making more informed and personalized treatment decisions based on an individual's genetic predispositions and responses to medications.

Healthcare Resource Optimization

Early intervention and prevention will reduce hospital admission rates, leading to more efficient resource allocation of healthcare resources.

Drug Development

Increased DNA data availability, along with electronic health records, will provide research scientists and pharmaceutical companies with more information to study gene-disease associations.

Employment Opportunity

Increased DNA setting in primary care setting will create job opportunities for specially trained genetic medicine physicians and genetic counsellors.